| Urokinase lyses recently formed pulmonary emboli and, compared with streptokinase, it produces fibrinolysis without extensive breakdown of the coagulation factors. |
| It is likely better to consider it as more fibrinolysis than clotting. |
| A total of 20,479 subjects for whom fibrinolysis was planned were randomised to a strategy of enoxaparin throughout the index hospitalization or UFH for 48 hours in a double-blind manner. |
| To answer this question, they first compared the levels of thrombin-activatable fibrinolysis inhibitor in bronchoalveolar fluid and in plasma. |
| Alteplase is a serine protease that binds to fibrin in a thrombus or blood clot resulting in conversion of plasminogen to plasmin and initiation of local fibrinolysis. |
| Therefore, fibrin derivatives in human blood or plasma containing D-dimer are a specific marker of fibrinolysis. |
