In normal somatic cells, the telomeres shorten with replicative age, and telomerase is not detected. |
At the back of your mind is the idea that a lightning flash triggered a replicative system in the primordial soup, and suddenly the show was on the road. |
When telomeres reach critically shortened length and a DNA damage signal is induced, a replicative senescence, or cell ageing, occurs. |
They possess a replicative mode of transposition, so that the insertions are mostly stable. |
This study demonstrates that a random approach reduced the replicative fitness of CHIKV in both primate and arthropod cells. |
We have a unique panel of cells from all stages of OSCC development, some which undergo replicative senescence and others which are immortal. |